Mouse Lrch1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Lrch1
Locus ID	380916
Kit Components	GA217049G1, Lrch1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA217049G2, Lrch1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA217049G3, Lrch1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001033439, NM_001252132
Synonyms	4832412D13Rik; AI552548; AW215503; Chdc1; mKIAA1016
Summary	Acts as a negative regulator of GTPase CDC42 by sequestering CDC42-guanine exchange factor DOCK8. Probably by preventing CDC42 activation, negatively regulates CD4(+) T-cell migration in response to chemokine stimulation.[UniProtKB/Swiss-Prot Function]

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