Mouse Poc1b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Poc1b
Locus ID	382406
Kit Components	GA217248G1, Poc1b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA217248G2, Poc1b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA217248G3, Poc1b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_027740, NR_153333
Synonyms	4933430F16Rik; Wdr51b
Summary	Plays an important role in centriole assembly and/or stability and ciliogenesis. Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Acts in concert with POC1A to ensure centriole integrity and proper mitotic spindle formation. Required for primary cilia formation, ciliary length and also cell proliferation. Required for retinal integrity.[UniProtKB/Swiss-Prot Function]

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