Mouse Zhx2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Zhx2
Locus ID	387609
Kit Components	GA217344G1, Zhx2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA217344G2, Zhx2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA217344G3, Zhx2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_199449
Synonyms	Afr-1; Afr1; mKIAA0854; Raf
Summary	Acts as a transcriptional repressor (PubMed:19515908). Represses the promoter activity of the CDC25C gene stimulated by NFYA (By similarity). May play a role in retinal development where it regulates the composition of bipolar cell populations, by promoting differentiation of bipolar OFF-type cells (PubMed:30146259). In the brain, may promote maintenance and suppress differentiation of neural progenitor cells in the developing cortex (PubMed:19515908).[UniProtKB/Swiss-Prot Function]

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