Mouse Cers3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cers3
Locus ID	545975
Kit Components	GA217821G1, Cers3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA217821G2, Cers3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA217821G3, Cers3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001164201
Synonyms	4930550L11Rik; Gm488; Lass3; T3L
Summary	Has (dihydro)ceramide synthesis activity with relatively broad substrate specificity, but a preference for C18:0 and other middle- to long-chain fatty acyl-CoAs. It is crucial for the synthesis of very long-chain ceramides in the epidermis, to maintain epidermal lipid homeostasis and terminal differentiation (By similarity).[UniProtKB/Swiss-Prot Function]

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