Activin A Receptor Type IB (ACVR1B) Human Gene Knockout Kit (CRISPR)

CAT#: KN206920BN

ACVR1B - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


Anti-ACVR1B rabbit polyclonal antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


ACVR1B (Myc-DDK-tagged)-Human activin A receptor, type IB (ACVR1B), transcript variant 1
    • 10 ug

CNY 3,760.00
CNY 3,990.00

Specifications

Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Donor DNA mBFP-Neo
Symbol Activin A Receptor Type IB
Locus ID 91
Kit Components

KN206920G1, Activin A Receptor Type IB gRNA vector 1 in pCas-Guide CRISPR vector

KN206920G2, Activin A Receptor Type IB gRNA vector 2 in pCas-Guide CRISPR vector

KN206920BN-D, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_004302, NM_020327, NM_020328
Synonyms ACTRIB; ACVRLK4; ALK4; SKR2
Summary This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents

Other Versions

其它Activin A Receptor Type IB产品

Customer Reviews 
Loading...