SOCS3 Human Gene Knockout Kit (CRISPR)

CAT#: KN209305RB

SOCS3 - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


SOCS3 mouse monoclonal antibody, clone OTI3D3 (formerly 3D3)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


SOCS3 (Myc-DDK-tagged)-Human suppressor of cytokine signaling 3 (SOCS3)
    • 10 ug

CNY 3,600.00
CNY 3,705.00

Specifications

Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Donor DNA RFP-BSD
Symbol SOCS3
Locus ID 9021
Kit Components

KN209305G1, SOCS3 gRNA vector 1 in pCas-Guide CRISPR vector

KN209305G2, SOCS3 gRNA vector 2 in pCas-Guide CRISPR vector

KN209305RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_003955
Synonyms ATOD4; CIS3; Cish3; SOCS-3; SSI-3; SSI3
Summary This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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