UNC5B Human Gene Knockout Kit (CRISPR)

CAT#: KN218267RB

UNC5B - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


Goat Anti-UNC5B (aa629-643) Antibody
    • 100 ug

CNY 5,371.00


UNC5B (Myc-DDK-tagged)-Human unc-5 homolog B (C. elegans) (UNC5B)
    • 10 ug

CNY 6,920.00
CNY 9,790.00

Specifications

Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Donor DNA RFP-BSD
Symbol UNC5B
Locus ID 219699
Kit Components

KN218267G1, UNC5B gRNA vector 1 in pCas-Guide CRISPR vector

KN218267G2, UNC5B gRNA vector 2 in pCas-Guide CRISPR vector

KN218267RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001244889, NM_170744
Synonyms p53RDL1; UNC5H2
Summary This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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