delta 2 Catenin (CTNND2) Human Gene Knockout Kit (CRISPR)

CAT#: KN224464LP

CTNND2 - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

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CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


CTNND2 rabbit polyclonal antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


CTNND2 (Myc-DDK-tagged)-Human catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) (CTNND2)
    • 10 ug

CNY 8,528.00

Specifications

Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Donor DNA Luciferase-Puro
Symbol delta 2 Catenin
Locus ID 1501
Kit Components

KN224464G1, delta 2 Catenin gRNA vector 1 in pCas-Guide CRISPR vector

KN224464G2, delta 2 Catenin gRNA vector 2 in pCas-Guide CRISPR vector

KN224464LP-D, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001288715, NM_001288716, NM_001288717, NM_001332, NR_109988, NM_001364128
Synonyms GT24; NPRAP
Summary This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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