S100A1 (NM_006271) Human Mass Spec Standard

Specifications

Product Data
Description	S100A1 MS Standard C13 and N15-labeled recombinant protein (NP_006262)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200278
Predicted MW	10.5 kDa
Protein Sequence	Sequence Link (showhide) >RC200278 protein sequence Red=Cloning site Green=Tags(s) MGSELETAMETLINVFHAHSGKEGDKYKLSKKELKELLQTELSGFLDAQKDVDAVDKVMKELDENGDGEV DFQEYVVLVAALTVACNNFFWENS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_006262
RefSeq Size	607
RefSeq ORF	282
Synonyms	S100; S100-alpha; S100A
Locus ID	6271
Cytogenetics	1q21.3
Summary	The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. [provided by RefSeq, Jul 2008]

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