PTP4A1 (NM_003463) Human Mass Spec Standard

Specifications

Product Data
Description	PTP4A1 MS Standard C13 and N15-labeled recombinant protein (NP_003454)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200435
Predicted MW	19.8 kDa
Protein Sequence	Sequence Link (showhide) >RC200435 protein sequence Red=Cloning site Green=Tags(s) MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPF DDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKRRGA FNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_003454
RefSeq Size	5093
RefSeq ORF	519
Synonyms	HH72; PRL-1; PRL1; PTP(CAAX1); PTPCAAX1
Locus ID	7803
Cytogenetics	6q12
Summary	This gene encodes a member of a small class of prenylated protein tyrosine phosphatases (PTPs), which contain a PTP domain and a characteristic C-terminal prenylation motif. The encoded protein is a cell signaling molecule that plays regulatory roles in a variety of cellular processes, including cell proliferation and migration. The protein may also be involved in cancer development and metastasis. This tyrosine phosphatase is a nuclear protein, but may associate with plasma membrane by means of its prenylation motif. Pseudogenes related to this gene are located on chromosomes 1, 2, 5, 7, 11 and X. [provided by RefSeq, Jun 2013]
Protein Families	Druggable Genome, Phosphatase

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