Emerin (EMD) (NM_000117) Human Mass Spec Standard

Specifications

Product Data
Description	EMD MS Standard C13 and N15-labeled recombinant protein (NP_000108)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200643
Predicted MW	29 kDa
Protein Sequence	Sequence Link (showhide) >RC200643 protein sequence Red=Cloning site Green=Tags(s) MDNYADLSDTELTTLLRRYNIPHGPVVGSTRRLYEKKIFEYETQRRRLSPPSSSAASSYSFSDLNSTRGD ADMYDLPKKEDALLYQSKGYNDDYYEESYFTTRTYGEPESAGPSRAVRQSVTSFPDADAFHHQVHDDDLL SSSEEECKDRERPMYGRDSAYQSITHYRPVSASRSSLDLSYYPTSSSTSFMSSSSSSSSWLTRRAIRPEN RAPGAGLGQDRQVPLWGQLLLFLVFVIVLFFIYHFMQAEEGNPF TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_000108
RefSeq Size	1370
RefSeq ORF	762
Synonyms	EDMD; LEMD5; STA
Locus ID	2010
Cytogenetics	Xq28
Summary	Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

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