CUEDC2 (NM_024040) Human Mass Spec Standard

Specifications

Product Data
Description	CUEDC2 MS Standard C13 and N15-labeled recombinant protein (NP_076945)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200790
Predicted MW	24.7 kDa
Protein Sequence	Sequence Link (showhide) >RC200790 protein sequence Red=Cloning site Green=Tags(s) MELERIVSAALLAFVQTHLPEADLSGLDEVIFSYVLGVLEDLGPSGPSEENFDMEAFTEMMEAYVPGFAH IPRGTIGDMMQKLSGQLSDARNKENLQPQSSGVQGQVPISPEPLQRPEMLKEETRSSAAAAADTQDEATG AEEELLPGVDVLLEVFPTCSVEQAQWVLAKARGDLEEAVQMLVEGKEEGPAAWEGPNQDLPRRLRGPQKD ELKSFILQKYMMVDSA TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_076945
RefSeq Size	1203
RefSeq ORF	678
Synonyms	bA18I14.5; C10orf66
Locus ID	79004
Cytogenetics	10q24.32
Summary	Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism.[UniProtKB/Swiss-Prot Function]

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