GMPR1 (GMPR) (NM_006877) Human Mass Spec Standard

Specifications

Product Data
Description	GMPR MS Standard C13 and N15-labeled recombinant protein (NP_006868)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC202453
Predicted MW	37.4 kDa
Protein Sequence	Sequence Link (showhide) >RC202453 protein sequence Red=Cloning site Green=Tags(s) MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQH SMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVE FVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAH GLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEVIERNGRKLKLFYGMSSDTAMNKHAG GVAEYRASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLKELSRRATFIRVTQQHNTVFS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_006868
RefSeq Size	1515
RefSeq ORF	1035
Synonyms	GMPR 1; GMPR1
Locus ID	2766
Cytogenetics	6p22.3
Summary	This gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. The protein also functions in the re-utilization of free intracellular bases and purine nucleosides.[provided by RefSeq, Oct 2009]
Protein Families	Druggable Genome
Protein Pathways	Purine metabolism

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