Troponin C (TNNC2) (NM_003279) Human Mass Spec Standard

Specifications

Product Data
Description	TNNC2 MS Standard C13 and N15-labeled recombinant protein (NP_003270)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC202754
Predicted MW	18.1 kDa
Protein Sequence	Sequence Link (showhide) >RC202754 protein sequence Red=Cloning site Green=Tags(s) MTDQQAEARSYLSEEMIAEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEEVDEDGSGT IDFEEFLVMMVRQMKEDAKGKSEEELAECFRIFDRNADGYIDPEELAEIFRASGEHVTDEEIESLMKDGD KNNDGRIDFDEFLKMMEGVQ TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_003270
RefSeq Size	698
RefSeq ORF	480
Synonyms	CFAP85; FAP85
Locus ID	7125
Cytogenetics	20q13.12
Summary	Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit. [provided by RefSeq, Jul 2008]
Protein Pathways	Calcium signaling pathway

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