FBXO31 (NM_024735) Human Mass Spec Standard

Specifications

Product Data
Description	FBXO31 MS Standard C13 and N15-labeled recombinant protein (NP_079011)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC203518
Predicted MW	41.7 kDa
Protein Sequence	Sequence Link (showhide) RC203518
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_079011
RefSeq Size	5990
RefSeq ORF	1617
Synonyms	FBX14; Fbx31; FBXO14; MRT45; pp2386
Locus ID	79791
Cytogenetics	16q24.2
Summary	This gene is a member of the F-box family. Members are classified into three classes according to the substrate interaction domain, FBW for WD40 repeats, FBL for leucing-rich repeats, and FBXO for other domains. This protein, classified into the last category because of the lack of a recognizable substrate binding domain, has been proposed to be a component of the SCF ubiquitination complex. It is thought to bind and recruit substrate for ubiquitination and degradation. This protein may have a role in regulating the cell cycle as well as dendrite growth and neuronal migration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Protein Families	Druggable Genome

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