Bone marrow stromal cell antigen 1 (BST1) (NM_004334) Human Mass Spec Standard

Specifications

Product Data
Description	BST1 MS Standard C13 and N15-labeled recombinant protein (NP_004325)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC204151
Predicted MW	35.7 kDa
Protein Sequence	Sequence Link (showhide) >RC204151 protein sequence Red=Cloning site Green=Tags(s) MAAQGCAASRLLQLLLQLLLLLLLLAAGGARARWRGEGTSAHLRDIFLGRCAEYRALLSPEQRNKNCTAI WEAFKVALDKDPCSVLPSDYDLFINLSRHSIPRDKSLFWENSHLLVNSFADNTRRFMPLSDVLYGRVADF LSWCRQKNDSGLDYQSCPTSEDCENNPVDSFWKRASIQYSKDSSGVIHVMLNGSEPTGAYPIKGFFADYE IPNLQKEKITRIEIWVMHEIGGPNVESCGEGSMKVLEKRLKDMGFQYSCINDYRPVKLLQCVDHSTHPDC ALKSAAAATQRKAPSLYTEQRAGLIIPLFLVLASRTQL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_004325
RefSeq Size	1497
RefSeq ORF	954
Synonyms	CD157
Locus ID	683
Cytogenetics	4p15.32
Summary	Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008]
Protein Families	Transmembrane
Protein Pathways	Calcium signaling pathway, Metabolic pathways, Nicotinate and nicotinamide metabolism

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