RBP4 (NM_006744) Human Mass Spec Standard

Specifications

Product Data
Description	RBP4 MS Standard C13 and N15-labeled recombinant protein (NP_006735)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC204635
Predicted MW	23 kDa
Protein Sequence	Sequence Link (showhide) >RC204635 protein sequence Red=Cloning site Green=Tags(s) MKWVWALFLLAALGSGRAERDCRVSSFRVKENFDKARFSGTWYAMAKKDPEGLFLQDNIVAEFSVDETGQ MSATAKGRVRLLNNWDVCADMVGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIVDTDYDTYAVQYSCRL LNLDGTCADSYSFVFSRDPNGLPPEAQKIVRQRQEELCLARQYRLIVHNGYCDGRSERNLL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_006735
RefSeq Size	941
RefSeq ORF	603
Synonyms	MCOPCB10; RDCCAS
Locus ID	5950
Cytogenetics	10q23.33
Summary	This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome, Secreted Protein

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