HSD17B6 (NM_003725) Human Mass Spec Standard

Specifications

Product Data
Description	HSD17B6 MS Standard C13 and N15-labeled recombinant protein (NP_003716)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC204701
Predicted MW	36 kDa
Protein Sequence	Sequence Link (showhide) >RC204701 protein sequence Red=Cloning site Green=Tags(s) MWLYLAAFVGLYYLLHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAACLTEKGAEQLR GQTSDRLETVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNLIG VIQVTLSMLPLVRRARGRIVNVSSILGRVAFFVGGYCVSKYGVEAFSDILRREIQHFGVKISIVEPGYFR TGMTNMTQSLERMKQSWKEAPKHIKETYGQQYFDALYNIMKEGLLNCSTNLNLVTDCMEHALTSVHPRTR YSAGWDAKFFFIPLSYLPTSLADYILTRSWPKPAQAV TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_003716
RefSeq Size	1629
RefSeq ORF	951
Synonyms	HSE; RODH; SDR9C6
Locus ID	8630
Cytogenetics	12q13.3
Summary	The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. [provided by RefSeq, Aug 2013]
Protein Families	Druggable Genome

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