CLTRN (NM_020665) Human Mass Spec Standard

Specifications

Product Data
Description	TMEM27 MS Standard C13 and N15-labeled recombinant protein (NP_065716)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC204775
Predicted MW	25.2 kDa
Protein Sequence	Sequence Link (showhide) >RC204775 protein sequence Red=Cloning site Green=Tags(s) MLWLLFFLVTAIHAELCQPGAENAFKVRLSIRTALGDKAYAWDTNEEYLFKAMVAFSMRKVPNREATEIS HVLLCNVTQRVSFWFVVTDPSKNHTLPAVEVQSAIRMNKNRINNAFFLNDQTLEFLKIPSTLAPPMDPSV PIWIIIFGVIFCIIIVAIALLILSGIWQRRRKNKEPSEVDDAEDKCENMITIENGIPSDPLDMKGGHIND AFMTEDERLTPL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_065716
RefSeq Size	1580
RefSeq ORF	666
Synonyms	NX-17; NX17; TMEM27
Locus ID	57393
Cytogenetics	Xp22.2
Summary	This gene encodes a type 1 transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. The encoded protein binds to amino acid transporters and regulates their expression on the plasma membrane. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells. The extracellular domain of the encoded protein may be cleaved and shed from the plasma membrane specifically in pancreatic beta cells. [provided by RefSeq, Jun 2013]
Protein Families	Transmembrane

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