RPB11 (POLR2J) (NM_006234) Human Mass Spec Standard

Specifications

Product Data
Description	POLR2J MS Standard C13 and N15-labeled recombinant protein (NP_006225)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC204819
Predicted MW	13.3 kDa
Protein Sequence	Sequence Link (showhide) >RC204819 protein sequence Red=Cloning site Green=Tags(s) MNAPPAFESFLLFEGEKKITINKDTKVPNACLFTINKEDHTLGNIIKSQLLKDPQVLFAGYKVPHPLEHK IIIRVQTTPDYSPQEAFTNAITDLISELSLLEERFRVAIKDKQEGIE TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_006225
RefSeq Size	991
RefSeq ORF	351
Synonyms	hRPB14; POLR2J1; RPB11; RPB11A; RPB11m
Locus ID	5439
Cytogenetics	7q22.1
Summary	This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene exists as a heterodimer with another polymerase subunit; together they form a core subassembly unit of the polymerase. Two similar genes are located nearby on chromosome 7q22.1 and a pseudogene is found on chromosome 7p13. [provided by RefSeq, Jul 2008]
Protein Families	Transcription Factors
Protein Pathways	Huntington's disease, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, RNA polymerase

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.