CHAC2 (NM_001008708) Human Mass Spec Standard

Specifications

Product Data
Description	CHAC2 MS Standard C13 and N15-labeled recombinant protein (NP_001008708)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC205083
Predicted MW	20.9 kDa
Protein Sequence	Sequence Link (showhide) >RC205083 protein sequence Red=Cloning site Green=Tags(s) MWVFGYGSLIWKVDFPYQDKLVGYITNYSRRFWQGSTDHRGVPGKPGRVVTLVEDPAGCVWGVAYRLPVG KEEEVKAYLDFREKGGYRTTTVIFYPKDPTTKPFSVLLYIGTCDNPDYLGPAPLEDIAEQIFNAAGPSGR NTEYLFELANSIRNLVPEEADEHLFALEKLVKERLEGKQNLNCI TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001008708
RefSeq Size	1305
RefSeq ORF	552
Synonyms	GCG1
Locus ID	494143
Cytogenetics	2p16.2
Summary	The protein encoded by this gene is a gamma-glutamyl cyclotransferase that catalyzes the conversion of glutathione to 5-oxoproline and cysteinylglycine. It is thought that this gene is upregulated in response to endoplasmic reticulum stress and that the glutathione depletion enhances apoptosis. [provided by RefSeq, Sep 2016]

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