DRC7 (NM_032269) Human Mass Spec Standard

Specifications

Product Data
Description	CCDC135 MS Standard C13 and N15-labeled recombinant protein (NP_115645)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC206168
Predicted MW	103.5 kDa
Protein Sequence	Sequence Link (showhide) >RC206168 protein sequence Red=Cloning site Green=Tags(s) MEVLREKVEEEEEAEREEAAEWAEWARMEKMMRPVEVRKEEITLKQETLRDLEKKLSEIQITVSAELPAF TKDTIDISKLPISYKTNTPKEEHLLQVADNFSRQYSHLCPDRVPLFLHPLNECEVPKFVSTTLRPTLMPY PELYNWDSCAQFVSDFLTMVPLPDPLKPPSHLYSSTTVLKYQKGNSFDFSTLLCSMLIGSGYDAYCVNGY GSLDLCHMDLTREVCPLTVKPKETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLRE EEERLMEAEKAKPDALHGLRVHSWVLVLSGKREVPENFFIDPFTGHSYSTQDEHFLGIESLWNHKNYWIN MQDCWNCCKDLIFDLGDPVRWEYMLLGTDKSQLSLTEEDDSGINDEDDVENLGKEDEDKSFDMPHSWVEQ IEISPEAFETRCLNGKKVIQYKRAKLEKWAPYLNSNGLVSRLTTYEDLQCTNILEIKEWYQNREDMLELK HINKTTDLKTDYFKPGHPQALRVHSYKSMQHEMDRVIEFYETARVDGLMKREETPRTMTEYYQGRPDFLS YRHASFGPRVKKLTLSSAESNPRPIVKITERFFRNPAKPAEEDVAERVFLVAEERIQLRYHCREDHITAS KREFLRRTEVDSKGNKIIMTPDMCISFEVEPMEHTKKLLYQYEAMMHLKREEKLSRHQVWESELEVLEIL KLREEEEAAHTLTISIYDTKRNEKSKEYREAMERMMHEEHLRQVETQLDYLAPFLAQLPPGEKLTCWQAV RLKDECLSDFKQRLINKANLIQARFEKETQELQKKQQWYQENQVTLTPEDEDLYLSYCSQAMFRIRILEQ RLNRHKELAPLKYLALEEKLYKDPRLGELQKIFA TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_115645
RefSeq Size	2926
RefSeq ORF	2622
Synonyms	C16orf50; CCDC135; CFAP50; FAP50
Locus ID	84229
Cytogenetics	16q21
Summary	Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Involved in the regulation of flagellar motility.[UniProtKB/Swiss-Prot Function]

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