ARRDC1 (NM_152285) Human Mass Spec Standard
CAT#: PH307160
ARRDC1 MS Standard C13 and N15-labeled recombinant protein (NP_689498)
View other "ARRDC1" proteins (3)
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CNY 19520.00
Specifications
Product Data | |
Description | ARRDC1 MS Standard C13 and N15-labeled recombinant protein (NP_689498) |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | RC207160 |
Predicted MW | 46 kDa |
Protein Sequence |
>RC207160 protein sequence
Red=Cloning site Green=Tags(s) MGRVQLFEISLSHGRVVYSPGEPLAGTVRVRLGAPLPFRAIRVTCIGSCGVSNKANDTAWVVEEGYFNSS LSLADKGSLPAGEHSFPFQFLLPATAPTSFEGPFGKIVHQVRAAIHTPRFSKDHKCSLVFYILSPLNLNS IPDIEQPNVASATKKFSYKLVKTGSVVLTASTDLRGYVVGQALQLHADVENQSGKDTSPVVASLLQKVSY KAKRWIHDVRTIAEVEGAGVKAWRRAQWHEQILVPALPQSALPGCSLIHIDYYLQVSLKAPEATVTLPVF IGNIAVNHAPVSPRPGLGLPPGAPPLVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLLATLS SVPGAPEPCPQDGSPASHPLHPPLCISTGATVPYFAEGSGGPVPTTSTLILPPEYSSWGYPYEAPPSYEQ SCGGVEPSLTPES TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Tag | C-Myc/DDK |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
Reference Data | |
RefSeq | NP_689498 |
RefSeq Size | 1621 |
RefSeq ORF | 1299 |
Locus ID | 92714 |
Cytogenetics | 9q34.3 |
Summary | Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates (PubMed:23886940, PubMed:27462458). Through an ubiquitination-dependent mechanism plays for instance a role in the incorporation of SLC11A2 into extracellular vesicles (PubMed:27462458). More generally, plays a role in the extracellular transport of proteins between cells through the release in the extracellular space of microvesicles (PubMed:22315426). By participating to the ITCH-mediated ubiquitination and subsequent degradation of NOTCH1, negatively regulates the NOTCH signaling pathway (PubMed:23886940).[UniProtKB/Swiss-Prot Function] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC407667 | ARRDC1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY407667 | Transient overexpression lysate of arrestin domain containing 1 (ARRDC1) |
CNY 3080.00 |
|
TP307160 | Recombinant protein of human arrestin domain containing 1 (ARRDC1), 20 µg |
CNY 2900.00 |