HIP2 (UBE2K) (NM_005339) Human Mass Spec Standard
CAT＃: PH308645
UBE2K MS Standard C13 and N15-labeled recombinant protein (NP_005330)
View other "HIP2" proteins (7)
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CNY 19520.00
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Specifications
| Product Data | |
| Description | UBE2K MS Standard C13 and N15-labeled recombinant protein (NP_005330) |
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC208645 |
| Predicted MW | 22.2 kDa |
| Protein Sequence |
>RC208645 representing NM_005339
Red=Cloning site Green=Tags(s) MANIAVQRIKREFKEVLKSEETSKNQIKVDLVDENFTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNP PKVRFITKIWHPNISSVTGAICLDILKDQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEM FKQTARLWAHVYAGAPVSSPEYTKKIENLCAMGFDRNAVIVALSSKSWDVETATELLLSN TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Reference Data | |
| RefSeq | NP_005330 |
| RefSeq Size | 2208 |
| RefSeq ORF | 600 |
| Synonyms | E2-25K; HIP2; HYPG; LIG; UBC1 |
| Locus ID | 3093 |
| Cytogenetics | 4p14 |
| Summary | The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Ubiquitin mediated proteolysis |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC417371 | UBE2K HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
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| LC426354 | UBE2K HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY417371 | Transient overexpression lysate of ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast) (UBE2K), transcript variant 1 |
CNY 3080.00 |
|
| LY426354 | Transient overexpression lysate of ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast) (UBE2K), transcript variant 3 |
CNY 3080.00 |
|
| TP308645 | Recombinant protein of human ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast) (UBE2K), transcript variant 1, 20 µg |
CNY 2900.00 |
|
| TP720163 | Recombinant protein of human ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast) (UBE2K), transcript variant 3 |
CNY 1800.00 |
|
| TP720982 | Purified recombinant protein of Human ubiquitin-conjugating enzyme E2K (UBE2K), transcript variant 1 |
CNY 1800.00 |
