Dermcidin (DCD) (NM_053283) Human Mass Spec Standard

Specifications

Product Data
Description	DCD MS Standard C13 and N15-labeled recombinant protein (NP_444513)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC209352
Predicted MW	11.3 kDa
Protein Sequence	Sequence Link (showhide) >RC209352 protein sequence Red=Cloning site Green=Tags(s) MRFMTLLFLTALAGALVCAYDPEAASAPGSGNPCHEASAAQKENAGEDPGLARQAPKPRKQRSSLLEKGL DGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSVL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_444513
RefSeq Size	645
RefSeq ORF	330
Synonyms	AIDD; DCD-1; DSEP; HCAP; PIF
Locus ID	117159
Cytogenetics	12q13.2
Summary	This antimicrobial gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
Protein Families	Secreted Protein

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