TSC22D3 (NM_004089) Human Mass Spec Standard

Specifications

Product Data
Description	TSC22D3 MS Standard C13 and N15-labeled recombinant protein (NP_004080)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC210088
Predicted MW	14.8 kDa
Protein Sequence	Sequence Link (showhide) >RC210088 protein sequence Red=Cloning site Green=Tags(s) MNTEMYQTPMEVAVYQLHNFSISFFSSLLGGDVVSVKLDNSASGASVVAIDNKIEQAMDLVKNHLMYAVR EEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLSPEEPAPESPQVPEAPGGSAV TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_004080
RefSeq Size	1986
RefSeq ORF	402
Synonyms	DIP; DSIPI; GILZ; TSC-22R
Locus ID	1831
Cytogenetics	Xq22.3
Summary	This gene encodes the anti-inflammatory protein glucocorticoid (GC)-induced leucine zipper. Expression of this gene stimulated by glucocorticoids and interleukin 10 and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid. This protein has also been shown to inhibit pro-inflammatory molecules including nuclear factor κB. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Protein Families	Transcription Factors

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