PF4 (NM_002619) Human Mass Spec Standard

Specifications

Product Data
Description	PF4 MS Standard C13 and N15-labeled recombinant protein (NP_002610)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC211322
Predicted MW	10.8 kDa
Protein Sequence	Sequence Link (showhide) >RC211322 protein sequence Red=Cloning site Green=Tags(s) MSSAAGFCASRPGLLFLGLLLLPLVVAFASAEAEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGPHCPTA QLIATLKNGRKICLDLQAPLYKKIIKKLLES TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_002610
RefSeq Size	878
RefSeq ORF	303
Synonyms	CXCL4; PF-4; SCYB4
Locus ID	5196
Cytogenetics	4q13.3
Summary	This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum. [provided by RefSeq, Oct 2014]
Protein Families	Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways	Chemokine signaling pathway, Cytokine-cytokine receptor interaction

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