SHFL (NM_018381) Human Mass Spec Standard

Specifications

Product Data
Description	C19orf66 MS Standard C13 and N15-labeled recombinant protein (NP_060851)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC212344
Predicted MW	32.9 kDa
Protein Sequence	Sequence Link (showhide) >RC212344 representing NM_018381 Red=Cloning site Green=Tags(s) MSQEGVELEKSVRRLREKFHGKVSSKKAGALMRKFGSDHTGVGRSIVYGVKQKDGQELSNDLDAQDPPED MKQDRDIQAVATSLLPLTEANLRMFQRAQDDLIPAVDRQFACSSCDHVWWRRVPQRKEVSRCRKCRKRYE PVPADKMWGLAEFHCPKCRHNFRGWAQMGSPSPCYGCGFPVYPTRILPPRWDRDPDRRSTHTHSCSAADC YNRREPHVPGTSCAHPKSRKQNHLPKVLHPSNPHISSGSTVATCLSQGGLLEDLDNLILEDLKEEEEEEE EVEDEEGGPRE TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_060851
RefSeq Size	1911
RefSeq ORF	873
Synonyms	C19orf66; IRAV; RyDEN; SFL
Locus ID	55337
Cytogenetics	19p13.2
Summary	Exhibits antiviral activity against dengue virus (DENV) and can inhibit the replication of all DENV serotypes. May block the protein translation of DENV RNA via its association with cellular mRNA-binding proteins and viral RNA. Can also limit the replication of hepatitis C virus (HCV), West Nile virus (WNV), Chikungunya virus (CHIKV), herpes simplex virus type 1 (HHV-1) and human adenovirus (PubMed:26735137).[UniProtKB/Swiss-Prot Function]

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