EIF4G1 (NM_004953) Human Mass Spec Standard

CAT#: PH312877

EIF4G1 MS Standard C13 and N15-labeled recombinant protein (NP_004944)



  View other "EIF4G1" proteins (7)

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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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Specifications

Product Data
Description EIF4G1 MS Standard C13 and N15-labeled recombinant protein (NP_004944)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC212877
Predicted MW 154.6 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_004944
RefSeq Size 5045
RefSeq ORF 4209
Synonyms EIF-4G1; EIF4F; EIF4G; EIF4GI; P220; PARK18
Locus ID 1981
Cytogenetics 3q27.1
Summary The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010]
Protein Pathways Viral myocarditis
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