Nardilysin (NRDC) (NM_002525) Human Mass Spec Standard

Specifications

Product Data
Description	NRD1 MS Standard C13 and N15-labeled recombinant protein (NP_002516)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC213239
Predicted MW	139.2 kDa
Protein Sequence	Sequence Link (showhide) RC213239
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_002516
RefSeq Size	3851
RefSeq ORF	3657
Synonyms	hNRD1; hNRD2; NRD1
Locus ID	4898
Cytogenetics	1p32.3
Summary	This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Protein Families	Druggable Genome, Protease

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