PYDC2 (NM_001083308) Human Mass Spec Standard

Specifications

Product Data
Description	PYDC2 MS Standard C13 and N15-labeled recombinant protein (NP_001076777)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC214665
Predicted MW	10.6 kDa
Protein Sequence	Sequence Link (showhide) >RC214665 representing NM_001083308 Red=Cloning site Green=Tags(s) MASSAELDFNLQALLEQLSQDELSKFKSLIRTISLGKELQTVPQTEVDKANGKQLVEIFTSHSCSYWAGM AAIQVFEKMNQTHLSGRADEHCVMPPP TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001076777
RefSeq Size	294
RefSeq ORF	291
Synonyms	cPOP2; POP2
Locus ID	152138
Cytogenetics	3q28
Summary	May play a role in innate immunity by disrupting the interaction between PYCARD and NLRP3, thereby regulating the NLRP3 inflammasome (PubMed:17339483, PubMed:17178784). May also inhibit NF-kappa-B signaling distally by affecting the nuclear accumulation of RELA (PubMed:17339483, PubMed:24871464).[UniProtKB/Swiss-Prot Function]

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