Amylin (IAPP) (NM_000415) Human Mass Spec Standard

Specifications

Product Data
Description	IAPP MS Standard C13 and N15-labeled recombinant protein (NP_000406)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC215074
Predicted MW	9.81 kDa
Protein Sequence	Sequence Link (showhide) >RC215074 representing NM_000415 Red=Cloning site Green=Tags(s) MGILKLQVFLIVLSVALNHLKATPIESHQVEKRKCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY GKRNAVEVLKREPLNYLPL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_000406
RefSeq Size	1462
RefSeq ORF	267
Synonyms	DAP; IAP
Locus ID	3375
Cytogenetics	12p12.1
Summary	This gene encodes a member of the calcitonin family of peptide hormones. This hormone is released from pancreatic beta cells following food intake to regulate blood glucose levels and act as a satiation signal. Human patients with type 1 and advanced type 2 diabetes exhibit reduced levels of the encoded hormone in blood and pancreas. This protein also exhibits a bactericidal, antimicrobial activity. [provided by RefSeq, Jul 2016]
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Maturity onset diabetes of the young

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