NAT8B (NM_016347) Human Mass Spec Standard

Specifications

Product Data
Description	NAT8B MS Standard C13 and N15-labeled recombinant protein (NP_057431)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC215647
Predicted MW	25.4 kDa
Protein Sequence	Sequence Link (showhide) >RC215647 representing NM_016347 Red=Cloning site Green=Tags(s) MAPYHIRKYQESDRKSVVGLLSGGMAEHAPATFRRLLKLPRTLILLLGGALALLLVSGSWILALVFSLSL LPALWFLAKKPWTRYVDIALRTDMSDITKSYLSECGSCFWVAESEEKVVGTVGALPVDDPTLREKRLQLF HLSVDNEHRGQGIAKALVRTVLQFARDQGYSEVVLDTSNIQLSAMGLYQSLGFKKTGQSFFHVWARLVDL HTVHFIYHLPSAQAGRL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_057431
RefSeq Size	845
RefSeq ORF	681
Synonyms	CML2; Hcml2; NAT8BP
Locus ID	51471
Cytogenetics	2p13.1
Summary	The protein encoded by this gene is highly similar to the N-acetyltransferase 8 (NAT8) gene product, which is a kidney and liver protein with homology to bacterial acetyltransferases involved in drug resistance. This gene is localized on chromosome 2 in the vicinity of the NAT8 gene and may represent a pseudogene of NAT8. This gene contains two polymorphic nonsense mutations that disrupt the active site of the protein. The full-length product of this gene contains a complete acetyltransferase domain and is identical in length to NAT8. [provided by RefSeq, Jul 2008]

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