DGKB (NM_004080) Human Mass Spec Standard

Specifications

Product Data
Description	DGKB MS Standard C13 and N15-labeled recombinant protein (NP_004071)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC217461
Predicted MW	90.4 kDa
Protein Sequence	Sequence Link (showhide) RC217461
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_004071
RefSeq Size	3926
RefSeq ORF	2412
Synonyms	DAGK2; DGK; DGK-BETA
Locus ID	1607
Cytogenetics	7p21.2
Summary	Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017]
Protein Families	Druggable Genome
Protein Pathways	Glycerolipid metabolism, Glycerophospholipid metabolism, Metabolic pathways, Phosphatidylinositol signaling system

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