CLIC1 (NM_001288) Human Mass Spec Standard

Specifications

Product Data
Description	CLIC1 MS Standard C13 and N15-labeled recombinant protein (NP_001279)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC218042
Predicted MW	26.7 kDa
Protein Sequence	Sequence Link (showhide) >RC218042 representing NM_001288 Red=Cloning site Green=Tags(s) MAEEQPQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYG TEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVL DNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIPEAFRGVHRYL SNAYAREEFASTCPDDEEIELAYEQVAKALK TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001279
RefSeq Size	1265
RefSeq ORF	723
Synonyms	CL1C1; CLCNL1; G6; NCC27
Locus ID	1192
Cytogenetics	6p21.33
Summary	Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome, Ion Channels: Other

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