LNK (SH2B3) (NM_005475) Human Mass Spec Standard

CAT#: PH318359

SH2B3 MS Standard C13 and N15-labeled recombinant protein (NP_005466)



  View other "LNK" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of SH2B adaptor protein 3 (SH2B3)
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SH2B3 (LNK) mouse monoclonal antibody, clone OTI2D8 (formerly 2D8)
    • 100 ul

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Specifications

Product Data
Description SH2B3 MS Standard C13 and N15-labeled recombinant protein (NP_005466)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC218359
Predicted MW 63 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_005466
RefSeq Size 5423
RefSeq ORF 1725
Synonyms IDDM20; LNK
Locus ID 10019
Cytogenetics 12q24.12
Summary This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
Protein Pathways Neurotrophin signaling pathway
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