Retinal S antigen (SAG) (NM_000541) Human Mass Spec Standard

CAT#: PH320057

SAG MS Standard C13 and N15-labeled recombinant protein (NP_000532)



  View other "Retinal S antigen" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
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Specifications

Product Data
Description SAG MS Standard C13 and N15-labeled recombinant protein (NP_000532)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC220057
Predicted MW 44.9 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_000532
RefSeq Size 1564
RefSeq ORF 1215
Synonyms RP47; S-AG
Locus ID 6295
Cytogenetics 2q37.1
Summary Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
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