PADI2 (NM_007365) Human Mass Spec Standard

CAT#: PH323889

PADI2 MS Standard C13 and N15-labeled recombinant protein (NP_031391)



  View other "PADI2" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of peptidyl arginine deiminase, type II (PADI2)
    • 100 ug

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Rabbit Polyclonal Anti-PADI2 Antibody
    • 50 ug

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Specifications

Product Data
Description PADI2 MS Standard C13 and N15-labeled recombinant protein (NP_031391)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC223889
Predicted MW 75.4 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_031391
RefSeq Size 2348
RefSeq ORF 1995
Synonyms PAD-H19; PAD2; PDI2
Locus ID 11240
Cytogenetics 1p36.13
Summary This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]
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