CD252 (TNFSF4) (NM_003326) Human Mass Spec Standard

Specifications

Product Data
Description	TNFSF4 MS Standard C13 and N15-labeled recombinant protein (NP_003317)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC224021
Predicted MW	20.9 kDa
Protein Sequence	Sequence Link (showhide) >RC224021 representing NM_003326 Red=Cloning site Green=Tags(s) MERVQPLEENVGNAARPRFERNKLLLVASVIQGLGLLLCFTYICLHFSALQVSHRYPRIQSIKVQFTEYK KEKGFILTSQKEDEIMKVQNNSVIINCDGFYLISLKGYFSQEVNISLHYQKDEEPLFQLKKVRSVNSLMV ASLTYKDKVYLNVTTDNTSLDDFHVNGGELILIHQNPGEFCVL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_003317
RefSeq Size	3510
RefSeq ORF	549
Synonyms	CD134L; CD252; GP34; OX-40L; OX4OL; TNLG2B; TXGP1
Locus ID	7292
Cytogenetics	1q25.1
Summary	This gene encodes a cytokine of the tumor necrosis factor (TNF) ligand family. The encoded protein functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells. Polymorphisms in this gene have been associated with Sjogren's syndrome and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Cytokine-cytokine receptor interaction

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