SETDB1 (NM_001145415) Human Mass Spec Standard
CAT＃: PH326620
SETDB1 MS Standard C13 and N15-labeled recombinant protein (NP_001138887)
View other "SETDB1" proteins (7)
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CNY 19520.00
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Specifications
| Product Data | |
| Description | SETDB1 MS Standard C13 and N15-labeled recombinant protein (NP_001138887) |
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC226620 |
| Predicted MW | 143 kDa |
| Protein Sequence |
>RC226620 representing NM_001145415
Red=Cloning site Green=Tags(s) MSSLPGCIGLDAATATVESEEIAELQQAVVEELGISMEELRHFIDEELEKMDCVQQRKKQLAELETWVIQ KESEVAHVDQLFDDASRAVTNCESLVKDFYSKLGLQYRDSSSEDESSRPTEIIEIPDEDDDVLSIDSGDA GSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDLHKGTLSQMSGELSKDGDLIVSMRILGKKRT KTWHKGTLIAIQTVGPGKKYKVKFDNKGKSLLSGNHIAYDYHPPADKLYVGSRVVAKYKDGNQVWLYAGI VAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKS GQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASALEKKQGQLRTRP NMGAVRSKGPVVQYTQDLTGTGTQFKPVEPPQPTAPPAPPFPPAPPLSPQAGDSDLESQLAQSRKQVAKK STSFRPGSVGSGHSSPTSPALSENVSGGKPGINQTYRSPLGSTASAPAPSALPAPPAPPVFHGMLERAPA EPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNPLLVPLLYDFRRMTARRRVNRKMGFHVIYKTP CGLCLRTMQEIERYLFETGCDFLFLEMFCLDPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTT PPPQVAYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRL EECLPTGVYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDD FADKEGLEMGDEYFANLDHIESVENFKEGYESDAPCSSDSSGVDLKDQEDGNSGTEDPEESNDDSSDDNF CKDEDFSTSSVWRSYATRRQTRGQKENGLSETTSKDSHPPDLGPPHIPVPPSIPVGGCNPPSSEETPKNK VASWLSCNSVSEGGFADSDSHSSFKTNEGGEGRAGGSRMEAEKASTSGLGIKDEGDIKQAKKEDTDDRNK MSVVTESSRNYGYNPSPVKPEGLRRPPSKTSMHQSRRLMASAQSNPDDVLTLSSSTESEGESGTSRKPTA GQTSATAVDSDDIQTISSGSEGDDFEDKKNMTGPMKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGES APVRKNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTE LTWDYNYEVGSVEGKELLCCCGAIECRGRLL TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Reference Data | |
| RefSeq | NP_001138887 |
| RefSeq ORF | 3873 |
| Synonyms | ESET; H3-K9-HMTase4; KG1T; KMT1E; TDRD21 |
| Locus ID | 9869 |
| Cytogenetics | 1q21.3 |
| Summary | This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.[provided by RefSeq, Jun 2011] |
| Protein Families | Druggable Genome |
| Protein Pathways | Lysine degradation |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC402212 | SETDB1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC428874 | SETDB1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1470.00 |
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| LY402212 | Transient overexpression lysate of SET domain, bifurcated 1 (SETDB1), transcript variant 2 |
CNY 3080.00 |
|
| LY428874 | Transient overexpression lysate of SET domain, bifurcated 1 (SETDB1), transcript variant 1 |
CNY 4840.00 |
|
| PH303647 | SETDB1 MS Standard C13 and N15-labeled recombinant protein (NP_036564) |
CNY 14250.00 |
|
| TP303647 | Purified recombinant protein of Homo sapiens SET domain, bifurcated 1 (SETDB1), transcript variant 2, 20 µg |
CNY 2900.00 |
|
| TP326620 | Recombinant protein of human SET domain, bifurcated 1 (SETDB1), transcript variant 1, 20 µg |
CNY 2900.00 |
