MyoGEF (PLEKHG6) (NM_001144857) Human Mass Spec Standard
CAT＃: PH327365
PLEKHG6 MS Standard C13 and N15-labeled recombinant protein (NP_001138329)
View other "MyoGEF" proteins (7)
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CNY 19520.00
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Specifications
| Product Data | |
| Description | PLEKHG6 MS Standard C13 and N15-labeled recombinant protein (NP_001138329) |
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC227365 |
| Predicted MW | 85.3 kDa |
| Protein Sequence |
>RC227365 representing NM_001144857
Red=Cloning site Green=Tags(s) MGCRLHAPGEKAAHDPSRRRLQQYVPFARGSGQARGLSPMRLRDPEPEKRHGGHVGAGLLHSPKLKELTK AHELEVRLHTFSMFGMPRLPPEDRRHWEIGEGGDSGLTIEKSWRELVPGHKEMSQELCHQQEALWELLTT ELIYVRKLKIMTDLLAAGLLNLQRVGLLMEVSAETLFGNVPSLIRTHRSFWDEVLGPTLEETRASGQPLD PIGLQSGFLTFGQRFHPYVQYCLRVKQTMAYAREQQETNPLFHAFVQWCEKHKRSGRQMLCDLLIKPHQR ITKYPLLLHAVLKRSPEARAQEALNAMIEAVESFLRHINGQVRQGEEQESLAAAAQRIGPYEVLEPPSDE VEKNLRPFSTLDLTSPMLGVASEHTRQLLLEGPVRVKEGREGKLDVYLFLFSDVLLVTKPQRKADKAKVI RPPLMLEKLVCQPLRDPNSFLLIHLTEFQCVSSALLVHCPSPTDRAQWLEKTQQAQAALQKLKAEEYVQQ KRELLTLYRDQDRESPSTRPSTPSLEGSQSSAEGRTPEFSTIIPHLVVTEDTDEDAPLVPDDTSDSGYGT LIPGTPTGSRSPLSRLRQRALRRDPRLTFSTLELRDIPLRPHPPDPQAPQRRSAPELPEGILKGGSLPQE DPPTWSEEEDGASERGNVVVETLHRARLRGQLPSSPTHADSAGESPWESSGEEEEEGPLFLKAGHTSLRP MRAEDMLREIREELASQRIEGAEEPRDSRPRKLTRAQLQRMRGPHIIQLDTPLSASEV TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Reference Data | |
| RefSeq | NP_001138329 |
| RefSeq ORF | 2274 |
| Synonyms | MyoGEF |
| Locus ID | 55200 |
| Cytogenetics | 12p13.31 |
| Summary | Guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. Also activates RHOG. Does not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving PLEKHG6, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.[UniProtKB/Swiss-Prot Function] |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC413270 | PLEKHG6 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1470.00 |
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| LC428528 | PLEKHG6 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1470.00 |
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| LC428529 | PLEKHG6 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1470.00 |
|
| LY413270 | Transient overexpression lysate of pleckstrin homology domain containing, family G (with RhoGef domain) member 6 (PLEKHG6), transcript variant 1 |
CNY 4840.00 |
|
| LY428528 | Transient overexpression lysate of pleckstrin homology domain containing, family G (with RhoGef domain) member 6 (PLEKHG6), transcript variant 2 |
CNY 4840.00 |
|
| LY428529 | Transient overexpression lysate of pleckstrin homology domain containing, family G (with RhoGef domain) member 6 (PLEKHG6), transcript variant 3 |
CNY 4840.00 |
|
| TP327365 | Recombinant protein of human pleckstrin homology domain containing, family G (with RhoGef domain) member 6 (PLEKHG6), transcript variant 3, 20 µg |
CNY 2900.00 |
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