HSP90AA1 / HSP90 alpha Human Protein
CAT#: AR03017PU-N
HSP90AA1 / HSP90 alpha human recombinant protein, 0.1 mg
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CNY 5050.00
货期*
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规格
Cited in 7 publications. |
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Concentration | lot specific |
Purity | >90% pure as determined by SDS-PAGE analysis (Purified by Multy-step Chromatography). |
Buffer | Presentation State: Purified State: Liquid protein Buffer System: 50 mM Tris pH 7.5, 5 mM Bme, 0.3M NaCl, 10% Glycerol |
Preparation | Liquid protein |
Applications | Western Blot Control, SDS-PAGE , ATPase Activity Assay, Surface Plasmon Resonance (SPR). Specificity: ~90 kDa |
Protein Description | Recombinant Hsp90 alpha cloned from a Human cDNA library |
Note | Centrifuge vial before opening. |
Storage | Store at 2-8°C for one week or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_001017963 |
Locus ID | 3320 |
UniProt ID | P07900 |
Cytogenetics | 14q32.31 |
Synonyms | HSP90A, HSPC1, HSPCA, Heat shock 86 kDa, HSP86, NY-REN-38, Heat shock protein HSP 90-alpha |
Summary | The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
Protein Families | Western Blot Control, &sub_category=Recombinant Proteins&families_filter=SDS-PAGE "> SDS-PAGE , &sub_category=Recombinant Proteins&families_filter= ATPase Activity Assay"> ATPase Activity Assay, Surface Plasmon Resonance (SPR). Specificity: ~90 kDa |
Protein Pathways | Antigen processing and presentation, NOD-like receptor signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer |
Citations (7)
The use of this Proteins has been cited in the following citations: |
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Coexposure to mercury increases immunotoxicity of trichloroethylene
,Gilbert KM, Rowley B, Gomez-Acevedo H, Blossom SJ,
Toxicol. Sci.
,PubMed ID 21084432
[HSP90AA1]
|
The rapid and direct determination of ATPase activity by ion exchange chromatography and the application to the activity of heat shock protein-90
,Bartolini M, Wainer IW, Bertucci C, Andrisano V,
J Pharm Biomed Anal
,PubMed ID 22497853
[HSP90AA1]
|
Targeting the Hsp90 C-terminal domain to induce allosteric inhibition and selective client downregulation
,Goode KM, Petrov DP, Vickman RE, Crist SA, Pascuzzi PE, Ratliff TL, Davisson VJ, Hazbun TR,
Biochim. Biophys. Acta
,PubMed ID 28495207
[HSP90AA1]
|
Oxidation and interaction of DJ-1 with 20S proteasome in the erythrocytes of early stage Parkinson's disease patients
,Saito Y, Akazawa-Ogawa Y, Matsumura A, Saigoh K, Itoh S, Sutou K, Kobayashi M, Mita Y, Shichiri M, Hisahara S, Hara Y, Fujimura H, Takamatsu H, Hagihara Y, Yoshida Y, Hamakubo T, Kusunoki S, Shimohama S, Noguchi N,
Sci Rep
,PubMed ID 27470541
[HSP90AA1]
|
Experimental Anti-Inflammatory Drug Semapimod Inhibits TLR Signaling by Targeting the TLR Chaperone gp96
,Wang J, Grishin AV, Ford HR,
J. Immunol.
,PubMed ID 27194788
[HSP90AA1]
|
Identification of new FGF1 binding partners-Implications for its intracellular function
,Bober J, Olsnes S, Kostas M, Bogacz M, Zakrzewska M, Otlewski J,
IUBMB Life
,PubMed ID 26840910
[HSP90AA1]
|
Chaxamycins A-D, bioactive ansamycins from a hyper-arid desert Streptomyces sp
,Rateb ME, Houssen WE, Arnold M, Abdelrahman MH, Deng H, Harrison WT, Okoro CK, Asenjo JA, Andrews BA, Ferguson G, Bull AT, Goodfellow M, Ebel R, Jaspars M,
J. Nat. Prod.
,PubMed ID 21553813
[HSP90AA1]
|
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