S100A8 / Calgranulin-A / MRP8 (1-93) Human Protein

Specifications

Product Data
Species	Human
Expression Host	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) MLTELEKALN SIIDVYHKYS LIKGNFHAVY RDDLKKLLET ECPQYIRKKG ADVWFKELDI NTDGAVNFQE FLILVIKMGV AAHKKSHEES HKE
Predicted MW	10.8 Da (93aa) confirmed by MALDI-TOF
Concentration	0.5mg/ml (determined by absorbance at 280nm)
Purity	> 90% by SDS-PAGE
Buffer	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Preparation	Liquid purified peptide
Applications	SDS-PAGE
Protein Description	Recombinant Human S100A8 was expressed in E.coli and purified by using conventional chromatography techniques.
Storage	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Stability	Shelf life: one year from despatch.
Reference Data
RefSeq	NP_002955.2
Locus ID	6279
UniProt ID	P05109
Cytogenetics	1q21.3
Synonyms	S100 calcium binding protein A8, Calgranulin-A, MRP-8, CFAG, CAGA, S100 calcium binding protein A8 60B8Ag, AI323541, B8Ag, BEE11, CAGA, Calprotectin L1L subunit, Calprotectin, included, CGLA, Chemotactic cytokine CP-10, CP-10, Cystic fibrosisantigen, L1Ag, Leukocyte L1 complex light chain, MA387, MIF, Migration inhibitory factor-related protein 8, Myeloid-related protein 8, Neutrophil cytosolic 7 kDa protein, NIF, p8, Pro-inflammatory S100 cytokine, Protein S100-A8, S100 calcium binding protein A8 (calgranulin A), S100A8, S100A8/S100A9 complex, included, urinary stone protein band A.
Summary	The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]

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