MCP1 / CCL2 (24-148, His-Tag) Mouse Protein

Specifications

Product Data
Species	Mouse
Expression Host	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) QPDAVNAPL TCCYSFTSKM IPMSRLESYK RITSSRCPKE AVVFVTKLKR EVCADPKKEW VQTYIKNLDR NQMRSEPTTL FKTASALRSS APLNVKLTRK SEANASTTFS TTTSSTSVGV TSVTVN
Tag	His-Tag
Predicted MW	16 kDa (146aa) confirmed by MALDI-TOF
Concentration	0.25mg/ml (determined by Bradford assay)
Purity	> 85% by SDS-PAGE
Buffer	Liquid in. Phosphate-Buffered Saline (pH 7.4) 10% glycerol
Applications	SDS-PAGE
Protein Description	Recombinant mouse CCL2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Storage	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Stability	Shelf life: one year from despatch.
Reference Data
RefSeq	NP_035463
Locus ID	20296
UniProt ID	P10148
Cytogenetics	11 49.82 cM
Synonyms	Chemokine (C-C motif) ligand 2, Monocyte chemoattractant protein 1, Monocyte chemotactic protein 1, MCP-1, Platelet-derived growth factor-inducible protein JE, Small-inducible cytokine A2, Je, Mcp1, Scya2, HC11, MCAF, Sigje, SMC-CF
Summary	This gene is one of several cytokine genes clustered on chromosome 11. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and memory T cells but not for neutrophils. The human ortholog has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis, and atherosclerosis. [provided by RefSeq, Sep 2015]

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