Endothelin B Receptor (EDNRB) (NM_000115) Human Recombinant Protein
CAT＃: TP304899
Recombinant protein of human endothelin receptor type B (EDNRB), transcript variant 1, 20 µg
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Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence |
>RC204899 protein sequence
Red=Cloning site Green=Tags(s) MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEIMTPPTKTLWPKGSNASLARSLAPAE VPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILI ASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIK GIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSF YFCLPLAITAFFYTLMTCEMLRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLY NQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSC LKFKANDHGYDNFRSSNKYSSS TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Predicted MW | 46.9 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_000106 |
| Locus ID | 1910 |
| UniProt ID | P24530 |
| Refseq Size | 4296 |
| Cytogenetics | 13q22.3 |
| Refseq ORF | 1326 |
| Synonyms | ABCDS; ET-B; ET-BR; ETB; ETB1; ETBR; ETRB; HSCR; HSCR2; WS4A |
| Summary | The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016] |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC400037 | EDNRB HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC418304 | EDNRB HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1470.00 |
|
| LC426542 | EDNRB HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY400037 | Transient overexpression lysate of endothelin receptor type B (EDNRB), transcript variant 1 |
CNY 3080.00 |
|
| LY418304 | Transient overexpression lysate of endothelin receptor type B (EDNRB), transcript variant 2 |
CNY 4840.00 |
|
| LY426542 | Transient overexpression lysate of endothelin receptor type B (EDNRB), transcript variant 3 |
CNY 3080.00 |
|
| PH304899 | EDNRB MS Standard C13 and N15-labeled recombinant protein (NP_000106) |
CNY 19520.00 |
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