RASGRP2 (NM_001098671) Human Recombinant Protein
CAT#: TP312719
Recombinant protein of human RAS guanyl releasing protein 2 (calcium and DAG-regulated) (RASGRP2), transcript variant 4, 20 µg
View other "RASGRP2" proteins (11)
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CNY 2900.00
CNY 6650.00
| Cited in 1 publication. | 
CNY 600.00
Specifications
| Product Data | |
| Species | Human | 
| Expression Host | HEK293T | 
| Expression cDNA Clone or AA Sequence | 
                 >RC212719 protein sequence 
Red=Cloning site Green=Tags(s) MAGTLDLDKGCTVEELLRGCIEAFDDSGKVRDPQLVRMFLMMHPWYIPSSQLAAKLLHIYQQSRKDNSNS LQVKTCHLVRYWISAFPAEFDLNPELAEQIKELKALLDQEGNRRHSSLIDIDSVPTYKWKRQVTQRNPVG QKKRKMSLLFDHLEPMELAEHLTYLEYRSFCKILFQDYHSFVTHGCTVDNPVLERFISLFNSVSQWVQLM ILSKPTAPQRALVITHFVHVAEKLLQLQNFNTLMAVVGGLSHSSISRLKETHSHVSPETIKLWEGLTELV TATGNYGNYRRRLAACVGFRFPILGVHLKDLVALQLALPDWLDPARTRLNGAKMKQLFSILEELAMVTSL RPPVQANPDLLSLLTVSLDQYQTEDELYQLSLQREPRSKSSPTSPTSCTPPPRPPVLEEWTSAAKPKLDQ ALVVEHIEKMVESVFRNFDVDGDGHISQEEFQIIRGNFPYLSAFGDLDQNQDGCISREEMVSYFLRSSSV LGGRMGFVHNFQESNSLRPVACRHCKALILGIYKQGLKCRACGVNCHKQCKDRLSVECRRRAQSVSLEGS APSPSPMHSHHHRAFSFSLPRPGRRGSRPPEIREEEVQTVEDGVFDIHL TRTRPLEQKLISEEDLAANDILDYKDDDDKV  | 
        
| Tag | C-Myc/DDK | 
| Predicted MW | 69.1 kDa | 
| Concentration | >0.05 µg/µL as determined by microplate BCA method | 
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining | 
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol | 
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. | 
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. | 
| Storage | Store at -80°C. | 
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. | 
| Reference Data | |
| RefSeq | NP_001092141 | 
| Locus ID | 10235 | 
| UniProt ID | Q7LDG7 | 
| Refseq Size | 2284 | 
| Cytogenetics | 11q13.1 | 
| Refseq ORF | 1827 | 
| Synonyms | CALDAG-GEFI; CDC25L | 
| Summary | The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2016] | 
| Protein Pathways | Chemokine signaling pathway, MAPK signaling pathway | 
Citations (1)
| The use of this Proteins has been cited in the following citations: | 
|---|
| 
                                                Memory B Cells Activate Brain-Homing, Autoreactive CD4+ T Cells in Multiple Sclerosis
                                                ,Jelcic, I;Al Nimer, F;Wang, J;Lentsch, V;Planas, R;Jelcic, I;Madjovski, A;Ruhrmann, S;Faigle, W;Frauenknecht, K;Pinilla, C;Santos, R;Hammer, C;Ortiz, Y;Opitz, L;Grönlund, H;Rogler, G;Boyman, O;Reynolds, R;Lutterotti, A;Khademi, M;Olsson, T;Piehl, F;Sospedra, M;Martin, R;,
                                                Cell
                                                ,PubMed ID 30173916
                                                [RASGRP2]
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Other Versions
| SKU | Description | Size | Price | 
|---|---|---|---|
| LC406966 | RASGRP2 HEK293T cell transient overexpression lysate (as WB positive control) | 
                                                     CNY 1470.00  | 
                                            |
| LC420662 | RASGRP2 HEK293T cell transient overexpression lysate (as WB positive control) | 
                                                     CNY 1470.00  | 
                                            |
| LC420663 | RASGRP2 HEK293T cell transient overexpression lysate (as WB positive control) | 
                                                     CNY 1470.00  | 
                                            |
| LY406966 | Transient overexpression lysate of RAS guanyl releasing protein 2 (calcium and DAG-regulated) (RASGRP2), transcript variant 2 | 
                                                     CNY 4840.00  | 
                                            |
| LY420662 | Transient overexpression lysate of RAS guanyl releasing protein 2 (calcium and DAG-regulated) (RASGRP2), transcript variant 3 | 
                                                     CNY 4840.00  | 
                                            |
| LY420663 | Transient overexpression lysate of RAS guanyl releasing protein 2 (calcium and DAG-regulated) (RASGRP2), transcript variant 4 | 
                                                     CNY 4840.00  | 
                                            |
| PH312672 | RASGRP2 MS Standard C13 and N15-labeled recombinant protein (NP_001092140) | 
                                                     CNY 19520.00  | 
                                            |
| PH312719 | RASGRP2 MS Standard C13 and N15-labeled recombinant protein (NP_001092141) | 
                                                     CNY 19520.00  | 
                                            |
| PH317525 | RASGRP2 MS Standard C13 and N15-labeled recombinant protein (NP_722541) | 
                                                     CNY 19520.00  | 
                                            |
| TP312672 | Recombinant protein of human RAS guanyl releasing protein 2 (calcium and DAG-regulated) (RASGRP2), transcript variant 3, 20 µg | 
                                                     
                                                        
                                                        
                                                        
                                                            CNY 2900.00  | 
                                            |
| TP317525 | Recombinant protein of human RAS guanyl releasing protein 2 (calcium and DAG-regulated) (RASGRP2), transcript variant 2, 20 µg | 
                                                     
                                                        
                                                        
                                                        
                                                            CNY 2900.00  | 
                                            
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