NIPP1 (PPP1R8) (NM_014110) Human Recombinant Protein
CAT＃: TP318843
Recombinant protein of human protein phosphatase 1, regulatory (inhibitor) subunit 8 (PPP1R8), transcript variant 1, 20 µg
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Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence |
>RC218843 protein sequence
Red=Cloning site Green=Tags(s) MAAAANSGSSLPLFDCPTWAGKPPPGLHLDVVKGDKLIEKLIIDEKKYYLFGRNPDLCDFTIDHQSCSRV HAALVYHKHLKRVFLIDLNSTHGTFLGHIRLEPHKPQQIPIDSTVSFGASTRAYTLREKPQTLPSAVKGD EKMGGEDDELKGLLGLPEEETELDNLTEFITAHNKRISTLTIEEGNLDIQRPKRKRKNSRVTFSEDDEII NPEDVDPSVGRFRNMVQTAVVPVKKKRVEGPGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSEAGSQPHG IHGTALIGGLPMPYPNLAPDVDLTPVVPSAVNMNPAPNPAVYNPEAVNEPKKKKYAKEAWPGKKPTPSLL I TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Predicted MW | 38.3 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_054829 |
| Locus ID | 5511 |
| UniProt ID | Q12972 |
| Refseq Size | 2377 |
| Cytogenetics | 1p35.3 |
| Refseq ORF | 1053 |
| Synonyms | ARD-1; ARD1; NIPP-1; NIPP1; PRO2047 |
| Summary | This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul 2008] |
| Protein Families | Druggable Genome, Transcription Factors |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC408577 | PPP1R8 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC415484 | PPP1R8 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY408577 | Transient overexpression lysate of protein phosphatase 1, regulatory (inhibitor) subunit 8 (PPP1R8), transcript variant 2 |
CNY 3080.00 |
|
| LY415484 | Transient overexpression lysate of protein phosphatase 1, regulatory (inhibitor) subunit 8 (PPP1R8), transcript variant 1 |
CNY 3080.00 |
|
| PH310575 | PPP1R8 MS Standard C13 and N15-labeled recombinant protein (NP_612568) |
CNY 19520.00 |
|
| PH318843 | PPP1R8 MS Standard C13 and N15-labeled recombinant protein (NP_054829) |
CNY 19520.00 |
|
| TP310575 | Recombinant protein of human protein phosphatase 1, regulatory (inhibitor) subunit 8 (PPP1R8), transcript variant 2, 20 µg |
CNY 2900.00 |
