Ataxin 3 (ATXN3) (NM_004993) Human Recombinant Protein
CAT＃: TP318923
Recombinant protein of human ataxin 3 (ATXN3), transcript variant 1, 20 µg
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Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence |
>RC218923 representing NM_004993
Red=Cloning site Green=Tags(s) MESIFHEKQEGSLCAQHCLNNLLQGEYFSPVELSSIAHQLDEEERMRMAEGGVTSEDYRTFLQQPSGNMD DSGFFSIQVISNALKVWGLELILFNSPEYQRLRIDPINERSFICNYKEHWFTVRKLGKQWFNLNSLLTGP ELISDTYLALFLAQLQQEGYSIFVVKGDLPDCEADQLLQMIRVQQMHRPKLIGEELAQLKEQRVHKTDLE RVLEANDGSGMLDEDEEDLQRALALSRQEIDMEDEEADLRRAIQLSMQGSSRNISQDMTQTSGTNLTSEE LRKRREAYFEKQQQKQQQQQQQQQQGDLSGQSSHPCERPATSSGALGSDLGDAMSEEDMLQAAVTMSLET VRNDLKTEGKK TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Predicted MW | 41.1 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_004984 |
| Locus ID | 4287 |
| UniProt ID | P54252 |
| Refseq Size | 2698 |
| Cytogenetics | 14q32.12 |
| Refseq ORF | 1083 |
| Synonyms | AT3; ATX3; JOS; MJD; MJD1; SCA3 |
| Summary | Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2016] |
| Protein Families | Druggable Genome, Transcription Factors |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC410754 | ATXN3 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC417607 | ATXN3 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC426854 | ATXN3 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC431255 | ATXN3 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC432176 | ATXN3 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY410754 | Transient overexpression lysate of ataxin 3 (ATXN3), transcript variant h |
CNY 3080.00 |
|
| LY417607 | Transient overexpression lysate of ataxin 3 (ATXN3), transcript variant reference |
CNY 3080.00 |
|
| LY426854 | Transient overexpression lysate of ataxin 3 (ATXN3), transcript variant ad |
CNY 3080.00 |
|
| LY431255 | Transient overexpression lysate of ataxin 3 (ATXN3), transcript variant y |
CNY 3080.00 |
|
| LY432176 | Transient overexpression lysate of ataxin 3 (ATXN3), transcript variant e |
CNY 3080.00 |
|
| PH318923 | ATXN3 MS Standard C13 and N15-labeled recombinant protein (NP_004984) |
CNY 19520.00 |
|
| TP710359 | Purified recombinant protein of Human ataxin 3 (ATXN3), transcript variant reference, full length, with with C-terminal DDK tag, expressed in sf9, 20ug |
CNY 4020.00 |
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