Fam45a (NM_026437) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR205446 protein sequence Red=Cloning site Green=Tags(s) MAAVVAMDTQLMLGVGLIEKDSSNGEALWVWCYPSTTASLRNLLLRKCCLTDENKLLHPFVFGQYRRTWF YVTTVEVPDSSVLKKVTHFSIVLTAKDFNPEKYAAFTRILCRIYLKYGSPVKMMESYIAVLTKGICQSEE NGSFLSRDFDGRKAYLAGSIKDIVSQFGMETVILHTALMLKKRIVVYHPKIEAVQEFTRTLPALVWHRQD WTILHSYMHLHAEELEGLQMCTGYIAGFVELEVSNRPDLYDVFVNLADSEITIAPLAKEAMTMGKLHKEI GQLIVQSAEDPEKSDSQVIQDIALKTKEIFTHLAPFSEVSDDGGKVILNVEALKQQRFPPATENFLYHLA AAEQMLKV TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	40.5 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_080713
Locus ID	67894
UniProt ID	Q9D8N2
Refseq Size	2366
Cytogenetics	19 D3
Refseq ORF	1074
Synonyms	1810055E12Rik
Summary	Guanine nucleotide exchange factor (GEF) regulating homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion, possibly through activating Rab proteins such as RAB27A and RAB27B. Seems to promote the exchange of GDP to GTP, converting inactive GDP-bound RAB27A and RAB27B into their active GTP-bound form.[UniProtKB/Swiss-Prot Function]

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