Fam83d (NM_027975) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR209141 protein sequence Red=Cloning site Green=Tags(s) MAARFELLDDLPAACLSPCGPPNPTELFSEARRLALEQLLAGGPDAWAAFLRRERLGRFLNADEVREVLG AAERPGEDGAAVAEDSFGSSHECSSGTYFPEQSDLEPPALELGWPSFYQGAYRGATRVEAHFQPRGAGAG GPYGCKDALRQQLRSAREVIAVVMDVFSDIDIFRDLQESCRKRGVAVYILLDQTLLPHFLDMCMDLRVHP EQEKLMTVRTITGNIYYARSGTKVVGKVHEKFTLIDGIRVATGSYSFTWTDGKLNSSNLVILSGQVVEHF DLEFRILYAQSEPISSKLLSNFQINSKFDHLADRKPQSKEPTLGNLLRMRLARLSSTPRKSNLGPEEPPK DRAKPKRPDSEASTISDEDYFHSHKDQLEDSKVADAATQTEPREEMAAVSLSEVGTQTSSSMMCVGTQTT VVTRAASSQATVWSKSTTTQTEADESFLPQGAQSKEGSPASKMSVSRSSSVRSSSSVSSQGSLASSVSSH VSLTAADLHTPAYPKYLGLGTPHLDLCLRDSFRNLSKERQVHFTGIRSRLTQMLTVLSRRTLFTEHYLSY SPGSFTRASTNLVSVRDIALYPPYQ TRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	64.3 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_082251
Locus ID	71878
UniProt ID	Q9D7I8
Refseq Size	2280
Cytogenetics	2 H1
Refseq ORF	1755
Synonyms	2310007D09Rik; BB104611
Summary	Probable proto-oncogene that regulates cell proliferation, growth, migration and epithelial to mesenchymal transition. Through the degradation of FBXW7, may act indirectly on the expression and downstream signaling of MTOR, JUN and MYC. May play also a role in cell proliferation through activation of the ERK1/ERK2 signaling cascade. May also be important for proper chromosome congression and alignment during mitosis through its interaction with KIF22.[UniProtKB/Swiss-Prot Function]

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